Fluoxetine was first patented by scientists from Eli Lilly and Company in 1977. It was approved for treatment of depression in Belgium in 1986 and in the U.S. in 1987. It was introduced as Prozac in 1994. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI), which means that it increases the availiability of serotonin, a neurotransmitter involved in mood regulation in the brain. The drug is marketed as Prozac to treat depression, obsessive-compulsive disorder, bulimia, and panic disorder, and as Sarafem to treat premenstrual dysphoric disorder.
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