Common molecules sample 50730

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Empirical formula:	C₂₂H₂₄N₂O₉
a:	8.836 Å
b:	12.416 Å
c:	18.760 Å
α (alpha):	90.00 °
β (beta):	90.00 °
γ (gamma):	90.00 °
Volume:	2058.12 Å³
Space group:	P212121
Calculated density:	1.486 g/cm³
Z:	4
Temperature:	-150.0 °C
Formula weight:	460.441 g/mole
R(F):	0.0540
Common name:	Oxytetracycline
Common name:	Tetracycline
CSD refcode:	OXYTET01
Short description:	Tetracycline is a common antibiotic.
Keyword:	antibiotic
Keyword:	teratogen
Citation of a publication:	Reference: J.Am.Chem.Soc.,99,(1977)p1117 Authors:R.Prewo, J.J.Stezowski
Layman's explanation:	Tetracycline was discovered by Lloyd H. Conover and patented by him in 1955. It was originally obtained from streptomyces viridifaciens cultures, but now is usually produced synthetically. Its most common use is as an antibiotic, but it is also used for many other medical purposes such as acne prevention. It works by inhibiting aminoacyl-tRNA binding during the synthesis of proteins. Tetracycline should not be used by children under nine or by women in the last half of a pregnancy as it is a teratogen and can cause reproductive problems. It can also cause photosensitivity in some people.
Lab name:	Common molecules
Sample provider:	Obtained courtesy of the Cambridge Structural Database
Status:	Complete, visible to public

Repository Files:
50730.cif	50730.crt	50730.GIF	50730.gif	50730.ort
50730.pdb	50730.sdt