R.W.Fuller, J.H.Cardellina II, Y.Kato,
L.S.Brinen, J.Clardy,
K.M.Snader, M.R.Boyd (1992)
J.Med.Chem.,35,3007
Layman's explanation:
Recently scientists have been searching various areas of the world for halomon,
a marine toxin, with attempts and hopes of creating a new treatment for cancer
and possibly HIV. Halomon is a naturally occurring, halogen-containing
compound that displays characteristics of anti-tumor activity. However, it is
difficult to obtain data on the biological activity of halomon
considering the limited amount available for testing. The NCI supports the
Coral Reef Research foundation in traveling to the Indopacifc region to search
for red algae to collect samples. When samples are collected, they are
immediately frozen until they can be used for screening purposes. While
screening, the Halomon is tested for certain types of cancer such as: leukemia,
melanoma, breast, central nervous system, colon, renal, and ovarian
cancers.
Lab name:
Common molecules
Sample provider:
Obtained courtesy of the Cambridge Structural Database
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