Common molecules sample 50969

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Empirical formula:	C₁₂H₁₈N₂O₇
a:	11.720 Å
b:	12.720 Å
c:	8.800 Å
α (alpha):	90.00 °
β (beta):	90.00 °
γ (gamma):	90.00 °
Volume:	1311.89 Å³
Space group:	P212121
Calculated density:	1.530 g/cm³
Z:	4
Temperature:	22.0 °C
Formula weight:	302.284 g/mole
R(F):	0.0700
Structural formula:	C₁₂H₁₈N₂O₇
Common name:	Bicyclomycin
CSD refcode:	BCYMYC
Short description:	Bicyclomycin is an antibacterial drug that acts as an inhibitor of the Rho transcription terminator factor.
Keyword:	antibiotics
Keyword:	Rho
Keyword:	transcription termination
Layman's explanation:	Bicyclomycin represents a unique class of antibiotics, discovered in 1972. It is obtained by the fermentation of Streptomyces sapporonensis. In the crystalline form bicyclomycin is observed to be rhombic or monoclinic, depending on the solvent used. This antibiotic kills bacteria by inhibiting the Rho transcription terminator factor, halting ribonucleic acid (RNA) synthesis. It is used to treat diarrhea in humans and non-specific diarrhea in animals, and is sold under the trade name of Bicozamycin or Bicoland.
Citation of a publication:	Y.Tokuma, S.Koda, T.Miyoshi, Y.Morimoto; Bull.Chem.Soc.Jpn., 47, (1974), 18
Lab name:	Common molecules
Sample provider:	Obtained courtesy of the Cambridge Structural Database
Status:	Complete, visible to public

Repository Files:
50969.cif	50969.crt	50969.GIF	50969.ort	50969.pdb
50969.sdt