Common molecules sample 51015

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Temperature:	4.0 °C
Common name:	Melittin
PDB entry #:	1BH1A or 1BH1
Keyword:	anti-bacterial
Keyword:	anti-inflammatory
Keyword:	bee venom
Short description:	Melittin is the main active toxin of bee venom.
Layman's explanation:	Melittin is a protein and the main active component of bee venom. The percentage level of its contents in bee venom is 50-60%. Melittin has a very strong anti-inflammatory and anti-bacterial effect. The protein has a small peptide with no disulphide bridge; the N-terminal part of the molecule is predominantly hydrophobic and the C-terminal part is hydrophilic and strongly basic. Recently, melittin peptides have been studied as potential toxins against prostate cancer. Also, antibody-melttin conjugates have been shown to selectively kill the tumor cells in vitro. Melittin may be fatal if it enters the bloodstream. It may cause allergic reaction (very low LD50s), which can act as a skin, eye or respiratory irritant. Melittin also helps to activate the body's adrenal glands, which causes one's own natural healing response. Many people that have multiple sclerosis (MS) use bee venom in order to help treat the disease.
Lab name:	Common molecules
Sample provider:	Obtained from the Protein Data Bank
Status:	Complete, visible to public

Repository Files:
51015.cif	51015.crt	51015.gif	51015.ort	51015.pdb
51015.sdt