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Common molecules sample 50715 - Reciprocal Net Log in
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Empirical formula: C13H19Cl1N1O11
a: 7.571 Å
b: 9.310 Å
c: 11.687 Å
α (alpha): 94.58 °
β (beta): 101.49 °
γ (gamma): 90.15 °
Volume: 804.54 Å3
Space group: P-1
Calculated density: 1.654 g/cm3
Z: 2
Temperature: 22.0 °C
Formula weight: 400.747 g/mole
R(F): 0.0560
Trade name: Wellbutrin
Common name: Bupropion
CSD refcode: NUFSOW
Short description: Bupropion is an anti-depressant of the amino-ketone class.
Keyword: smoking cessation
Keyword: antidepressant
Citation of a publication: Reference: J.Chem.Inf.Comput.Sci., #38(1998)p506 Authors: M.Froimowitz, C.George
IUPAC name: N-t-Butyl-1-(3-chlorobenzoyl)ethylammonium salt
Layman's explanation: N.B. Mehta and D.A. Yeowell of the Wellcome Foundation, Ltd. first patented bupropion HCl as an antidepressant in 1971. Since then, the drug has been marketed under the names Wellbutrin and Zyban. Bupropion works by an unknown mechanism, but is involved in the dopaminergic and noradrenergic systems. It is a weak inhibitor of neuronal uptake of norepinephrine, serotonin, and dopamine. Bupropion is marketed as Wellbutrin for the treatment of depression and attention deficit disorder and as Zyban (in stustained release form) for help in smoking cessation.
Lab name: Common molecules
Sample provider: Obtained courtesy of the Cambridge Structural Database
Status: Complete, visible to public
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