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Common molecules sample 50722 - Reciprocal Net Log in
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Empirical formula: C5H4N4S1, H2O
a: 15.294 Å
b: 7.732 Å
c: 12.379 Å
α (alpha): 90.00 °
β (beta): 101.64 °
γ (gamma): 90.00 °
Volume: 1433.75 Å3
Space group: C2/c
Z: 8
Temperature: 22.0 °C
R(F): 0.0380
CSD refcode: MERPUM
Common name: 6-Mercaptopurine
Common name: Mercaptopurine monohydrate
Short description: Mercaptopurine is an anti-cancer agent.
Keyword: leukemia
Keyword: anti-cancer
Empirical formula - less solvent: C5H4N4S1
Citation of a publication: Reference:(1969)Acta Crystallogr.Sect.B, 25 (1969)p1330 Authors:E.Sletten, J.Sletten, L.H.Jensen
Layman's explanation: Gertrude B. Elion invented 6-mercaptopurine (6MP) in 1954 as a leukemia-fighting drug while she was working on antagonists of nucleic acid building blocks. 6MP is converted to thioinosinic acid by the enzyme hypoxanthine-guanine phosphoribosyltransferase, thus inhibiting RNA synthesis. Mercaptopurine is a drug that is used to treat certain types of cancer and leukemia. There are many side effects to this drug such as reduction of bone marrow, liver function, ulcers, and diarrhea.
Lab name: Common molecules
Sample provider: Obtained courtesy of the Cambridge Structural Database
Status: Complete, visible to public
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