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Common molecules sample 50845 - Reciprocal Net Log in
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a: 67.400 Å
b: 67.400 Å
c: 290.100 Å
α (alpha): 90.00 °
β (beta): 90.00 °
γ (gamma): 120.00 °
Volume: 1473400.70 Å3
Space group: P6522
Z: 12
PDB entry #: 5PEP
Common name: Pepsin
Short description: Pepsin is an acidic protease that acts within the digestive system.
Keyword: protease
Keyword: digestion
Keyword: enzyme
Citation of a publication: Cooper, J.B.; Khan, G.; Taylor, G.; Tickle, I.J.; Blundell, T.L. X-Ray Analysis of Aspartic Proteases. Three Dimensional Structure of the Hexagonal Crystal Form of Porcine Pepsin at 2.3 Angstroms Resolution. J. Mol. Biol. 214 (1990) p199.
Copyright notice: null
Layman's explanation: Pepsin is one of many enzymes that digest proteins. The active site groove within pepsin binds proteins, cleaves certain bonds, and releases the pieces. These smaller molecules are further digested by other proteases and peptidases, eventually forming molecules which are useful as fuel for cells or for the biosynthesis of proteins. In order to avoid the digestion of all proteins near pepsin, this digestive protein is only active when outside the cell and at a specific pH.
Lab name: Common molecules
Sample provider: Obtained from the Protein Data Bank
Status: Complete, visible to public
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