Salinamide B is produced by the marine bacterium Streptomyces, an actinomycete
that has been isolated from the surface of the jellyfish Cassiopeia xamachana,
collected from the Florida Keys. Salinamide B shows moderate antibiotic
activity against Gram-positive bacteria and exhibits potent topical
anti-inflammatory activity. The biosynthesis of salinamide is currently being
studied with hopes of generating unnatural salinamide analogues, which would be
used to further understand its anti-inflammatory properties. Salinamide is
thought to be a possible contender in the treatment of some forms of arthritis.
Lab name:
Common molecules
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Obtained courtesy of the Cambridge Structural Database
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