Common molecules sample 50530

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Empirical formula:	C₁₀H₁₆N₂O₃S₁
a:	5.241 Å
b:	10.345 Å
c:	21.042 Å
α (alpha):	90.00 °
β (beta):	90.00 °
γ (gamma):	90.00 °
Volume:	1140.86 Å³
Space group:	P2₁2₁2₁
Calculated density:	2.845 g/cm³
Color:	colorless
Z:	8
Temperature:	20.0 °C
Formula weight:	244.315 g/mole
R(F):	0.0530
Common name:	Biotin
CSD refcode:	BIOTIN01
Common name:	Vitamin H
Short description:	Vitamin H is water-soluble and belongs to the group of essential B vitamins.
Keyword:	biotin
Keyword:	avidin
Layman's explanation:	Vitamin H, or biotin, was discovered by Vincent du Vigneaud and his colleagues in 1942. They noticed that when farm animals were fed raw eggs, they developed a biotin deficiency. Avidin, a protein in raw eggs, binds to biotin and inhibits its enzymatic activity. Biotin binds to the active site of pyruvate carboxylase, which promotes the formation of glucose. Sources of biotin include cooked eggs, liver, wheat bran, and yeast. Deficiencies arise from consuming too many raw eggs, which contain avidin.
Citation of a publication:	Reference: J. Am. Chem. Soc. 98 (1976) p1920 Authors: G. T. DeTitta, J. W. Edmonds, W. Stallings, J. Donohue
Lab name:	Common molecules
Sample provider:	Obtained courtesy of the Cambridge Structural Database
Status:	Complete, visible to public

Repository Files:
50530.crt	50530.gif	50530.GIF	50530.ort	50530.pdb
50530.sdt	50530.tab	50530.xtel