Pepsin is an acidic protease that acts within the digestive system.
Keyword:
protease
Keyword:
digestion
Keyword:
enzyme
Citation of a publication:
Cooper, J.B.; Khan, G.; Taylor, G.; Tickle,
I.J.; Blundell, T.L. X-Ray Analysis of
Aspartic Proteases. Three Dimensional
Structure of the Hexagonal Crystal Form of
Porcine Pepsin at 2.3 Angstroms Resolution.
J. Mol. Biol. 214 (1990) p199.
Copyright notice:
null
Layman's explanation:
Pepsin is one of many enzymes that digest proteins. The active site groove within pepsin binds proteins, cleaves certain bonds, and releases the pieces. These smaller molecules are further digested by other proteases and peptidases, eventually forming molecules which are useful as fuel for cells or for the biosynthesis of proteins. In order to avoid the digestion of all proteins near pepsin, this digestive protein is only active when outside the cell and at a specific pH.
Reciprocal Net site software 0.9.1-50,
copyright (c) 2002-2009, The Trustees of Indiana University
Files and data presented via this software are property of their
respective owners.
Reciprocal Net is funded by the U.S. National Science Foundation as part of
the National Science Digital Library project.
