Common molecules sample 50681

Empirical formula:	C₂₇H₄₆O₁
a:	14.172 Å
b:	34.209 Å
c:	10.481 Å
α (alpha):	94.64 °
β (beta):	90.67 °
γ (gamma):	96.32 °
Volume:	5032.77 Å³
Space group:	P1
Calculated density:	1.021 g/cm³
Z:	8
Formula weight:	386.662 g/mole
R(F):	0.0570
Common name:	Cholesterol
CSD refcode:	CHOEST20
Short description:	Cholesterol is a steroid alcohol (sterol) important to animal cell structure and related to coronary health.
Keyword:	lipoprotein
Keyword:	HDL
Keyword:	LDL
Citation of a publication:	Reference: Acta Crystallographica, (1981), B37, pp1538-44 Authors: H.-S. Shieh, L.G. Hoard, and C.E. Nordman
Layman's explanation:	Cholesterol prevents hydrocarbons from crystallizing during phase shifts in a membrane. Cholesterol also immobilizes the first hydrocarbon groups of phospholipid molecules making them less deformable and less permeable. High density lipoproteins (HDL) carry away the low density lipoproteins (LDL) which build up in the arteries. The liver manufactures about 80% of the human body s cholesterol. The other 20% comes from consuming animal products. Cholesterol is stored in the body s plasma membranes. High levels of cholesterol (LDL), 240+ mg/dL, cause hardening of arteries. The arterial build-up reduces the flow of oxygen to the heart and often results in heart disease. It is also important to have enough HDL cholesterol, as it helps to flush away the LDL from the arteries.
Lab name:	Common molecules
Sample provider:	Obtained courtesy of the Cambridge Structural Database
Status:	Complete, visible to public

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